孙雄华

研究内容

抗肺纤维化活性成分的发现及机制研究

学习经历

1996/09-2000/06，山东医科大学，拉斯维加斯登录网站3133，学士

2003/09-2006/06，中国药科大学，生命科学与技术学院，硕士

2007/09-2013/06，我校，医学院，博士

工作经历

2000/08－至今，拉斯维加斯登录网站3133拉斯维加斯登录网站3133，助教，讲师，副教授

发表论文

1. Mei Zhu, Jian Zhang, Xionghua Sun^*, Xihua Chen, Xiaogang Jiang^*. Eupafolin suppresses TGF-β1-induced human lung fibroblasts differentiation by downregulating β-catenin/plasminogen activator inhibitor-1 signaling. Pharmacological Research-Modern Chinese Medicine, 2022, 2, 100056.

2. Xiafang Xu^#, Xionghua Sun^#, Xuelei Wan, Xihua Chen, Xiaogang Jiang. Mitomycin induces alveolar epithelial cell senescence by down-regulating GSK3β signaling. Toxicology Letters, 2021, 352, 61-69.

3. Xionghua Sun, Mei Zhu, Xihua Chen, Xiaogang Jiang.MYH9 inhibition suppresses TGF-β1-stimulated lung fibroblast-to-myofibroblast differentia-

tion.Frontiers in Pharmacology,2021, 11, 573524.

4. Xionghua Sun^#, Xinjian Cui^#, Xihua Chen, Xiaogang Jiang.Baicalein alleviated TGF β1-induced type I collagen production in lung fibroblasts via downregulation of connective tissue growth factor. Biomedicine &  Pharmacotherapy,2020, 131, 110744.

5. Fanqing Lu^#, Xionghua Sun^#, Xiafang Xu, Xiaogang Jiang.SILAC-based proteomic profiling of the suppression of TGF-β1-induced lung fibroblast-to-myofibroblast differentiation by trehalose. Toxicologyand Applied Pharmacology, 2020, 391, 114916.

6. Xinjian Cui^#, Xionghua Sun^#, Fanqing Lu, Xiaogang Jiang. Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21. Toxicologyand Applied Pharmacology,2018, 358, 35-42.

7. Xiang Zhou^#, Xionghua Sun^#, Xiaogang Jiang. Comparative proteome profiling of bleomycin-induced lung toxicity in rats by 2D-nano-LC-MS/MS and spectral counting. Biomedical Chromatography, 2017, 31，e3857.

8. Xionghua Sun, Xiaogang Jiang.Automated platform of μLC-MS/MS using SAX trap column for highly efficient phosphopeptide analysis. Analytical and Bioanalytical Chemistry,2017, 409, 2489-2493.

9. Xionghua Sun, Xiaogang Jiang.Combination of FASP and fully automated 2D-LC-MS/MS allows in-depth proteomic characterization of mouse zymogen granules. Biomedical Chromatography, 2013, 27, 407-408.

10 .Xionghua Sun, Zhaoyue Wang，Haiyan Yang，Lijuan Cao，Jian Su，Ziqiang Yu，Xia Bai，Changgeng Ruan. Clinical, pathological, and genetic analysis of ten patients with MYH9-related disease，Acta Haematologica, 2013, 129, 106~113.